drugset / Trial / NCT02498756

Cytokine-induced Killer Study for Patients With Stage II Melanoma

NCT02498756

Phase 2 Not yet recruiting 300 enrolled The First People's Hospital of Changzhou
RandomizedParallel-groupOpen-labelTreatment

Summary

For investigators' current experimental clinical trial, patients are given 4 injections of ipilimumab, given 3 weeks apart x 4 injections with or without cytokine-induced killer therapy. Investigators propose to test this dual therapy in patients with melanoma who have known stage I, metastatic melanoma. Investigators hypothesize that this form of combinatorial immunotherapy will result in tumor stabilization or shrinkage, significant prolongation of progression-free, disease-free or overall survival compared to the use of ipilimumab alone

Timeline

Start
2015-08
Primary completion
2038-08
Completion
2040-08

Drugs

EvaluationDrugModalityDoseRoute
Subject CIK cells Cell therapy Intravenous
Subject Ipilimumab Monoclonal antibody

Indications