drugset / Trial / NCT02500940
Comparison the Effects of Different Neoadjuvant Chemotherapy Regimen on Acute Toxicity, Tumor Response, and Survival in Patients With Advanced Nasopharyngeal Carcinoma
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to investigate the impact of different neoadjuvant chemotherapy schedules of cisplatin and 5-FU on acute toxicity, tumor response, and long-term survival in patients with advanced nasopharyngeal carcinoma
Timeline
- Start
- 2015-05
- Primary completion
- 2016-05
- Completion
- 2021-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cisplatin | Other / unclassified | 60 mg/m2 | — |
| Subject | Cisplatin | Other / unclassified | 100 mg/m2 | — |
| Comparator | Leucovorin | Small molecule | 250 mg/m2 | — |
| Subject | fluorouracil | Small molecule | 1000 mg/m2 | Intravenous |
| Subject | fluorouracil | Small molecule | 2500 mg/m2 | Intravenous |