drugset / Trial / NCT02501018

Study to Assess the Efficacy and Safety of CLBS12 in Patients with Critical Limb Ischemia (CLI)

NCT02501018

Phase 2 Completed 33 enrolled Lisata Therapeutics, Inc.
RandomizedParallel-groupOpen-labelTreatment

Summary

A prospective, open label, controlled, randomized, double arm, multi-center study to assess the efficacy and safety of CLBS12 in patients with critical limb ischemia (CLI) due to arteriosclerosis obliterans (ASO) with a single arm sub-study to assess the safety and potential efficacy of CLBS12 in patients with CLI due to Buerger's Disease (BD).

Timeline

Start
2017-11-01
Primary completion
2022-05-19
Completion
2022-05-19

Drugs

EvaluationDrugModalityDoseRoute
Subject rHIV7-shI-TAR-CCR5RZ-transduced Hematopoietic Stem/Progenitor Cells Unknown 1e+06 cells/kg Intramuscular