Regorafenib, C-kit Mutated Malignant Melanoma, 2nd Line Therapy

Summary

This is a phase II trial of regorafenib in patients with metastatic melanoma harboring c-Kit mutations and/or amplifications of c-Kit gene copy number. The primary end point is disease control rate (DCR), and the secondary end points are safety, response rate (RR), progression free survival (PFS), and overall survival (OS).

Timeline

Start

2015-02

Primary completion

2022-05

Completion

2022-06

Drugs

Indications