drugset / Trial / NCT02503709

Onalespib and CDKI AT7519 in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

NCT02503709

Phase 1 Completed 29 enrolled National Cancer Institute (NCI)
NaSingle-groupOpen-labelTreatment

Summary

This phase I trial studies the side effects and best dose of onalespib and CDKI AT7519 in treating patients with solid tumors that have spread from the primary site (place where they started) to other places in the body (metastatic) or cannot be removed by surgery. Onalespib and CDKI AT7519 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Timeline

Start
2016-09-30
Primary completion
2020-08-15
Completion
2020-10-09

Drugs

EvaluationDrugModalityDoseRoute
Subject AT7519 Small molecule Intravenous
Subject Onalespib Small molecule Intravenous