drugset / Trial / NCT02507479

Thiotepa-based Conditioning for Allogeneic Stem-cell Transplantation (SCT) in Lymphoid Malignancies

NCT02507479

Phase 2 Unknown 24 enrolled Sheba Medical Center
NaSingle-groupOpen-labelTreatment

Summary

The study hypotheses is that the introduction of dose escalated thiotepa, in substitution to busulfan or melphalan, will reduce toxicity after allogeneic transplantation while improving disease eradication in patients with lymphoid malignancies not eligible for standard transplantation.

Timeline

Start
2015-09
Primary completion
2017-07
Completion
2019-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Thiotepa Other / unclassified 5 mg/kg Intravenous
Subject Thiotepa Other / unclassified 10 mg/kg Intravenous