drugset / Trial / NCT02509858

The Effect of Administration of Small Doses of Thyroxine on Glucose and Lipid Metabolism, in Type 2 Diabetes Mellitus.

NCT02509858

Completed 33 enrolled Attikon Hospital
RandomizedCrossoverOpen-labelTreatment

Summary

We investigated the effect of the administration of small doses of thyroxine to healthy humans and patients with type 2 diabetes on postprandial forearm muscle glucose uptake, insulin sensitivity indices, lipid metabolism, in vitro glucose uptake and GLUT4 recruitment in the plasma membrane of monocytes.

Timeline

Start
2009-02
Primary completion
2014-02
Completion
2015-07

Drugs

EvaluationDrugModalityDoseRoute
Comparator Levothyroxine Other / unclassified 50 ug

Indications