TBE (Tick-borne Encephalitis) Vaccination in Allergic Patients

Phase 4 Completed 119 enrolled Medical University of Vienna

Non-randomizedParallel-groupOpen-labelPrevention

Summary

Allergic patients especially those undergoing de-sensitization treatment have an altered immune responsiveness. The investigators aim to find out whether this influences immune responses to primary and booster vaccinations.

Timeline

Start: 2013-09
Primary completion: 2016-02
Completion: 2016-09

Publications

Garner-Spitzer E, Seidl-Friedrich C, Zwazl I, Hofer M, Kinaciyan T, Jarisch R, Stiasny K, Zlabinger GJ, Kundi M, Wiedermann U. Allergic patients with and without allergen-specific immunotherapy mount protective immune responses to tick-borne encephalitis vaccination in absence of enhanced side effects or propagation of their Th2 bias. Vaccine. 2018 May 11;36(20):2816-2824. doi: 10.1016/j.vaccine.2018.03.076. Epub 2018 Apr 16.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	FSME-Immun® (Fruehsommer-Meningoencephalitis)	Unknown	0.5 ml	—

Indications

No indication recorded.