drugset / Trial / NCT02521376

Pharmacokinetics of Entospletinib in Adults With Normal and Impaired Liver Function

NCT02521376

Phase 1 Completed 56 enrolled Gilead Sciences
Non-randomizedParallel-groupOpen-labelTreatment

Summary

The primary objective of this study is to evaluate the pharmacokinetics of entospletinib (ENTO) and/or its metabolites (if applicable) in participants with impaired hepatic function (stratified by smoking status, as appropriate) relative to matched, healthy controls.

Timeline

Start
2015-11-16
Primary completion
2017-10-25
Completion
2017-10-25

Drugs

EvaluationDrugModalityDoseRoute
Subject Entospletinib Small molecule 100 mg Oral

Indications

No indication recorded.