drugset / Trial / NCT02522117
Atorvastatin in the Recipient's Kidney Graft From a Living Donor
RandomizedParallel-groupDouble-blindTreatment
Summary
Renal insufficiency is a priority disease in the health system, which may require renal replacement therapy based on kidney transplantation, which is considered as therapy of choice. During the procedure of kidney transplantation, the body is subjected to ischemia-reperfusion damage that generates late complications related to graft function. Recently the anti-inflammatory and immunomodulatory effects of statins have been emphasized, which could be beneficial in kidney transplantation.
Timeline
- Start
- 2015-08
- Primary completion
- 2016-12
- Completion
- 2018-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Atorvastatin | Small molecule | 40 mg | Oral |