Evaluating Alternative Medical Therapies in Primary Hyperparathyroidism

Summary

This study will evaluate whether blocking the mineralocorticoid receptor, alone, or in combination with the calcimimetic cinacalcet, can lower parathyroid hormone and calcium levels in primary hyperparathyroidism.

Timeline

Start

2016-01

Primary completion

2021-10-01

Completion

2021-10-02

Outcome

Missed primary endpoint

registry analysis (superiority test); Eplerenone vs Placebo; p = 0.84; Median Difference (Net) 3.2; ANOVA NCT02525796 ↗

Drugs

Indications