drugset / Trial / NCT02528318

Trial To Assess The Safety And Tolerability Of Lucinactant For Inhalation In Preterm Neonates 26 to 28 Weeks PMA

NCT02528318

Phase 2 Terminated 48 enrolled Windtree Therapeutics
RandomizedSequentialOpen-labelTreatment

Summary

This study is to evaluate the safety and tolerability of lucinactant for inhalation, administered as an aerosol in up to four escalating doses to preterm neonates 26 to 28 weeks gestational age who are receiving nCPAP for RDS compared to neonates receiving nCPAP alone.

Timeline

Start
2015-08
Primary completion
2017-05-31
Completion
2017-08-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Lucinactant Peptide 50 mg/kg Other
Subject Lucinactant Peptide 75 mg/kg Other
Subject Lucinactant Peptide 100 mg/kg Other
Subject Lucinactant Peptide 150 mg/kg Other