drugset / Trial / NCT02533219

Study of the Use of [18F]-DOPA in Hyperinsulinemic Hypoglycemia

NCT02533219

Expanded access No longer available Baylor College of Medicine

Summary

The primary objective of this study is to evaluate the utility of \[18F\]-DOPA PET to provide improved presurgical planning and distinguish between focal and diffuse forms of HI. The investigators will perform descriptive analysis, relying on visual analysis to diagnose and localize a focal lesion. Our findings will be compared to surgical histopathology to determine sensitivity and specificity or this technique. The investigators will also track patient surgical outcomes, specifically whether the patient is surgically "cured" or still requires medical management to control residual hypoglycemia.

Timeline

Start
Primary completion
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject 18F-DOPA Diagnostic / imaging agent 2.96 mbq/kg
Subject 18F-DOPA Diagnostic / imaging agent 5.92 mbq/kg