drugset / Trial / NCT02536430

Efficacy of Ketorolac Buccal Infiltration on Success Rate of Inferior Alveolar Nerve Block

NCT02536430

Phase 2 Completed 40 enrolled Nahid Mohammadzadeh Akhlaghi
RandomizedParallel-groupTriple-blindTreatment

Summary

The aim of this study was to determine whether combining an intraoral injection of a non steroidal anti-inflammatory drug (Ketorolac), in association with conventional inferior alveolar nerve block, would improve the success rate in teeth with irreversible pulpitis. Forty adult volunteers with including criteria has been randomly divided into two groups (n=20). All patients received standard inferior alveolar nerve block injection. After achieving the lip numbness, one group received a buccal infiltration of Ketorolac and the other one received a buccal infiltration of Normal Saline as placebo. Any pain during root canal treatment has been recorded using analog visual scale. The success was considered as none or mild pain during treatment. The data have been analyzed using Mann-U-Whitney and chi-squared tests.

Timeline

Start
2015-03
Primary completion
2015-06
Completion
2015-08

Drugs

EvaluationDrugModalityDoseRoute
Comparator Ketorolac Tromethamine Small molecule 30 mg/ml Other

Indications

No indication recorded.