drugset / Trial / NCT02537600

Vemurafenib and Cobimetinib Combination in BRAF Mutated Melanoma With Brain Metastasis

NCT02537600

Phase 2 Completed 43 enrolled Center Eugene Marquis
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to determine wether cobimetinib + vemurafenib combination treatment is effective in the treatment of BRAFV600-mutated melanoma patients with brain metastasis

Timeline

Start
2015-12
Primary completion
2019-11-06
Completion
2019-11-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Cobimetinib Small molecule 60 mg Oral
Subject Vemurafenib Small molecule 960 mg Oral

Indications