drugset / Trial / NCT02537847

Sitafloxacin and Ertapenem Treatment for Acute Pyelonephritis Caused by Escherichia Coli

NCT02537847

Phase 2 Unknown 96 enrolled Mahidol University
RandomizedParallel-groupOpen-labelTreatment

Summary

The aim of the investigators' study was to evaluate oral and non carbapenem antimicrobial agents which can be used in outpatient for the treatment of non-bacteremic acute pyelonephritis caused by Extended Spectrum Beta Lactamase Escherichia coli. This study was conducted to compare the clinical and bacteriological outcomes of patients with non-bacteremic acute pyelonephritis caused by Extended Spectrum Beta Lactamase Escherichia coli who were treated with intravenous (IV) carbapenems followed by oral sitafloxacin or IV ertapenem.

Timeline

Start
2012-11
Primary completion
2015-09
Completion
2016-05

Drugs

EvaluationDrugModalityDoseRoute
Comparator Ertapenem Small molecule Intravenous
Subject SITAFLOXACIN ANHYDROUS Small molecule 100 mg Oral