drugset / Trial / NCT02538367

Phase 1/2a Trial of YH12852 in Healthy Subjects and Patients With Functional Constipation

NCT02538367

Phase 1/2 Completed 120 enrolled Yuhan Corporation
RandomizedParallel-groupDouble-blind

Summary

A randomized, double-blind/open-label, placebo/active-controlled, single/multiple dose, parallel, phase 1/2a trial to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of YH12852 in healthy subjects and patients with functional constipation

Timeline

Start
2015-08
Primary completion
2016-09
Completion
2016-09

Drugs

EvaluationDrugModalityDoseRoute
Comparator Prucalopride Small molecule 2 mg
Subject YH12852 Unknown 0.05 mg
Subject YH12852 Unknown 0.1 mg
Subject YH12852 Unknown 0.3 mg
Subject YH12852 Unknown 0.5 mg
Subject YH12852 Unknown 1 mg
Subject YH12852 Unknown 2 mg
Subject YH12852 Unknown 3 mg
Subject YH12852 Unknown 4 mg
Subject YH12852 Unknown 8 mg

Indications