drugset / Trial / NCT02540876

Ilorasertib in Treating Patients With CDKN2A-deficient Advanced or Metastatic Solid Cancers That Cannot Be Removed by Surgery

NCT02540876

NaSingle-groupOpen-labelTreatment

Summary

This pilot phase I trial studies how well ilorasertib works in treating patients with cyclin-dependent kinase inhibitor 2A (CDKN2A)-deficient solid cancers that have spread to other places in the body and usually cannot be cured or controlled with treatment (advanced) or have spread to other places in the body (metastatic) and cannot be removed by surgery. Ilorasertib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Timeline

Start
2015-09-08
Primary completion
2019-02-08
Completion
2019-02-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Ilorasertib Small molecule Oral