drugset
drugset / Trial / NCT02545452

Effect of Concomitant Use of an Antimycotic, an Antibiotic, a Spermicide or Tampons on Pharmacokinetics of Anastrozole and Levonorgestrel Released From Intra-vaginal Ring

NCT02545452 ↗

Phase 1 Completed 52 enrolled Bayer
RandomizedParallel-groupOpen-labelDiagnostic

Summary

To investigate the pharmacokinetic effect of a vaginally administered antimycotic (miconazole), antibiotic (clindamycin), spermicide (nonoxynol-9) or the concomitant use of tampons during the use of an intravaginal ring releasing anastrozole and levonorgestrel

Timeline

Start
2015-09-15
Primary completion
2016-03-14
Completion
2016-07-29

Drugs

EvaluationDrugModalityDoseRoute
Subject Anastrozole Other / unclassified 1050 ug Other
Subject Clindamycin Unknown 100 mg Other
Subject Levonorgestrel Small molecule 40 ug Other
Subject Miconazole Small molecule 400 mg Other
Subject Nonoxynol-9 Small molecule 75 mg Other

Indications

endometriosis