Efficacy and Safety of LEO 43204 in Field Treatment of Actinic Keratosis on Face or Chest Including 12-month Follow-up

Summary

The objective of the trial is to compare the short term efficacy of LEO 43204 gel with vehicle gel in AK on face or chest when applied topically once daily for 3 consecutive days as field treatment.

Timeline

Start

2015-11

Primary completion

2016-11

Completion

2017-11

Outcome

Met primary endpoint

registry analysis (superiority test); LEO 43204 0.018% Gel vs Vehicle Gel; p <0.001; Ratio of clearance rates 30.55 (95% CI 4.28 to 218.0); Mantel Haenszel NCT02547233 ↗

Drugs

Indications