drugset / Trial / NCT02548390

Study of Intravenous RXDX-107 in Patients With Solid Tumors

NCT02548390 ↗

Phase 1 Terminated 70 enrolled Hoffmann-La Roche
NaSingle-groupOpen-labelTreatment

Summary

This is an open-label, Phase I/Ib, dose escalation study of intravenous RXDX-107 administered to subjects with advanced solid tumors. The study is designed to explore the safety, maximum tolerated dose (MTD), pharmacokinetics, pharmacodynamics, and preliminary clinical activity of RXDX-107 and to define a recommended Phase 2 dose (RP2D)

Timeline

Start
2015-09
Primary completion
2016-09
Completion
2016-09

Outcome

Outcome not reported

Stopped: “Company decision”

Drugs

EvaluationDrugModalityDoseRoute
Subject BENDAMUSTINE DODECYL ESTER Small molecule 25 mg/m2 Intravenous

Indications