drugset / Trial / NCT02549924

Effect of Administration of Resveratrol on Glycemic Variability in Individuals With Type 2 Diabetes Mellitus

NCT02549924

Phase 2 Terminated 22 enrolled University of Guadalajara
RandomizedParallel-groupDouble-blindTreatment

Summary

Type 2 diabetes mellitus \[ T2DM \] has quickly become the epidemic of the XXI century and challenging global health . Estimates of the World Health Organization \[ WHO \] indicate that globally , from 1995 to date has nearly tripled the number of people living with diabetes mellitus \[DM \]. Resveratrol has been extensively studied as a regulator of glucose through its antioxidant effects and protecting pancreatic β cells by activation of sirtuin -1 \[ SIRT1 \] dependent deacetylase nicotinamide adenine diphosphate \[ NAD \]. Therefore, it is important to know the effect of resveratrol on the glycemic variability \[GV \] in patients with T2DM who are not in control with metformin monotherapy based.

Timeline

Start
2016-09
Primary completion
2018-01-01
Completion
2018-02-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Resveratrol Small molecule 500 mg