drugset / Trial / NCT02556320

Immunological and Viral Parameters in Patients Receiving Anti-epileptic Drugs

NCT02556320 ↗

Completed 30 enrolled University Hospital, Rouen
NaSingle-groupOpen-labelDiagnostic

Summary

A recent study has shown that certain drug allergies were actually related to an immune system against certain viruses. The aim of the study is to evaluate, in patients taking antiepileptic drugs, if this treatment induces proliferation of these viruses and secondarily an immune response that would promote the development of a rash. In particular, will be studied whether these drugs can induce virus reactivation "dormant" in the immune system. This study will not affect the usual follow-up proposed by investigators, with the exception of some additional blood samples.

Timeline

Start
2013-05
Primary completion
2015-08
Completion
2015-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Carbamazepine Small molecule — —
Subject Eslicarbazepine acetate Unknown — —
Subject Lamotrigine Small molecule — —
Subject Oxcarbazepine Small molecule — —
Subject Valproate Small molecule — —
Subject divalproate sodium Unknown — —
Subject valpromide Small molecule — —

Indications