A Study to Evaluate the Efficacy & Safety of an Intra-Articular Ampion Injection for Pain of Osteoarthritis of the Knee

Phase 3 Completed 480 enrolled Ampio Pharmaceuticals. Inc.

RandomizedParallel-groupDouble-blindTreatment

This study will evaluate the efficacy and safety of an intra-articular injection of AMPION™ in adults with pain due to osteoarthritis of the knee

Missed primary endpoint

registry analysis (superiority test); 4 mL AMPION™ vs 4 mL Saline Placebo; p = 0.94; ANCOVA NCT02556710 ↗

Evaluation	Drug	Modality	Dose	Route
Subject	ASPARTYL-ALANYL-DIKETOPIPERAZINE	Protein / enzyme biologic	4 ml	Other