drugset / Trial / NCT02563951
Study of Granisetron Hydrochloride Nasal Spray (GNS) in Healthy Volunteers
Phase 1
Completed
50 enrolled
Maxinase Life Sciences Ltd.
Tri-Service General Hospital (TSGH) · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to examine the pharmacokinetics (PK), safety and tolerability of 3 intranasal (IN) doses (0.5, 1.0 and 2.0 mg) of Granisetron Hydrochloride Nasal Sprays (GNS) as compared to Granisetron IV Injection and Granisetron Tablet in healthy Volunteers.
Timeline
- Start
- 2015-09
- Primary completion
- 2015-12
- Completion
- 2015-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Granisetron | Other / unclassified | 0.5 mg | Intranasal |
| Comparator | Granisetron | Other / unclassified | 1 mg | Intranasal |
| Comparator | Granisetron | Other / unclassified | 1 mg | Intravenous |
| Comparator | Granisetron | Other / unclassified | 2 mg | Intranasal |