drugset / Trial / NCT02568800
Prolonged Infusion Cefepime and Nosocomial Infections
RandomizedParallel-groupOpen-labelTreatment
Summary
It is advocated that prolonged infusion of beta-lactamic antibiotics provides better bactericidal effect. The aim of the present study is to randomize patients a to extended cefepime infusion regimen (lasting four hours) or to a usual infusion regimen (not lasting more than thirty minutes) and evaluate the clinical efficacy of this theoretical pharmacokinetic advantage.
Timeline
- Start
- 2015-10
- Primary completion
- 2016-03
- Completion
- 2016-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cefepime | Small molecule | — | — |