drugset / Trial / NCT02568800

Prolonged Infusion Cefepime and Nosocomial Infections

NCT02568800

Phase 3 Unknown 134 enrolled Hospital de Clinicas de Porto Alegre
RandomizedParallel-groupOpen-labelTreatment

Summary

It is advocated that prolonged infusion of beta-lactamic antibiotics provides better bactericidal effect. The aim of the present study is to randomize patients a to extended cefepime infusion regimen (lasting four hours) or to a usual infusion regimen (not lasting more than thirty minutes) and evaluate the clinical efficacy of this theoretical pharmacokinetic advantage.

Timeline

Start
2015-10
Primary completion
2016-03
Completion
2016-09

Drugs

EvaluationDrugModalityDoseRoute
Subject Cefepime Small molecule