drugset / Trial / NCT02570841
Pain Thresholds Under High-dose Topical Capsaicin
RandomizedCrossoverQuadruple-blindPrevention
Summary
Aim of the study is to determine heat pain thresholds (HPT in °C) and cold pain thresholds (CPT in °C) during topical capsaicin 8% application, and mechanical pain thresholds (MPT in g) immediately after to find out the exact skin temperature by which capsaicin initiates the application pain (heat pain threshold, HPT in °C) but also the temperature by which capsaicin does not yet trigger a cold pain (cold pain threshold, CPT in °C). Moreover the investigators want to find out the mechanical pain threshold in g from topical capsaicin and to verify a prolonged effect of capsaicin on the pain thresholds.
Timeline
- Start
- 2015-02
- Primary completion
- 2015-05
- Completion
- 2015-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Capsaicin | Small molecule | 8 % | Topical |
Indications
No indication recorded.