drugset / Trial / NCT02570841

Pain Thresholds Under High-dose Topical Capsaicin

NCT02570841

RandomizedCrossoverQuadruple-blindPrevention

Summary

Aim of the study is to determine heat pain thresholds (HPT in °C) and cold pain thresholds (CPT in °C) during topical capsaicin 8% application, and mechanical pain thresholds (MPT in g) immediately after to find out the exact skin temperature by which capsaicin initiates the application pain (heat pain threshold, HPT in °C) but also the temperature by which capsaicin does not yet trigger a cold pain (cold pain threshold, CPT in °C). Moreover the investigators want to find out the mechanical pain threshold in g from topical capsaicin and to verify a prolonged effect of capsaicin on the pain thresholds.

Timeline

Start
2015-02
Primary completion
2015-05
Completion
2015-09

Drugs

EvaluationDrugModalityDoseRoute
Comparator Capsaicin Small molecule 8 % Topical

Indications

No indication recorded.