drugset / Trial / NCT02576912

Testing the Interactive Effects of Delta-9-Tetrahydrocannabinol and Pregnenolone

NCT02576912

Phase 1 Completed 38 enrolled Yale University
RandomizedCrossoverQuadruple-blindBasic science

Summary

The overall purpose of this study is to examine the effect of pregnenolone (PREG) on the acute psychosis-like and cognitive effects of Delta-9-tetrahydrocannabinol (THC). This will be tested by pretreating healthy individuals with PREG and then assessing their responses to THC.

Timeline

Start
2015-02
Primary completion
2019-06-24
Completion
2019-06-24

Drugs

EvaluationDrugModalityDoseRoute
Subject Dronabinol Other / unclassified 0.036 mg/kg Intravenous
Subject Pregnenolone Other / unclassified Subcutaneous

Indications

No indication recorded.