drugset / Trial / NCT02579187
MicroRNA and MicroRNA Inhibitors Socket Study, Pilot Clinical Trial
RandomizedParallel-groupSingle-blindHealth-services research
Summary
To evaluate the efficacy of locally delivering plasmid DNAs encoding microRNAs, and/or microRNA inhibitors, in the promotion of osteogenesis and modulation of the inflammatory response on the basis of different clinical, radiographic, histologic and biomolecular outcomes in post-extraction socket defects in humans.
Timeline
- Start
- 2025-12-31
- Primary completion
- 2030-09
- Completion
- 2030-09
Outcome
Outcome not reported
Stopped: “withdrawn study from IRB”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | PMIS miR200a | Other / unclassified | 5 ug | Other |
| Comparator | PMIS miR200a | Other / unclassified | 10 ug | Other |
| Comparator | pSil-miR200c | Other / unclassified | 5 ug | Other |
| Comparator | pSil-miR200c | Other / unclassified | 10 ug | Other |
Indications
No indication recorded.