drugset / Trial / NCT02581124

Study to Evaluate Effect of Lapatinib on Pharmacokinetics of JTZ-951 in Subjects With End-stage Renal Disease

NCT02581124

Phase 1 Completed 10 enrolled Akros Pharma Inc.
NaSingle-groupOpen-labelTreatment

Summary

Study to evaluate the effect of lapatinib, a breast cancer resistance protein (BCRP) inhibitor, on the pharmacokinetics (PK) of JTZ-951 and to evaluate the safety and tolerability of JTZ-951 when administered alone and one hour after the administration of lapatinib.

Timeline

Start
2015-10
Primary completion
2016-04
Completion
2016-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Enarodustat Small molecule
Subject Lapatinib Small molecule