Study Evaluating Intepirdine (RVT-101) in Subjects With Mild to Moderate Alzheimer's Disease on Donepezil: MINDSET Study

Summary

This study seeks to confirm a demonstrated treatment effect of intepirdine (RVT-101) as an adjunctive therapy to donepezil for the treatment of subjects with Alzheimer's disease.

Timeline

Start

2015-10

Primary completion

2017-09

Completion

2017-09

Outcome

Missed primary endpoint

registry analysis (superiority test); RVT-101 vs Placebo; p = 0.2249 NCT02585934 ↗

registry analysis (superiority test); RVT-101 vs Placebo; p = 0.8260 NCT02585934 ↗

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	intepirdine	Small molecule	35 mg	Oral

Indications