drugset / Trial / NCT02590003

Single Agent Versus Combination Chemotherapy to Treat High-risk Elderly With Non-small Cell Lung Cancer

NCT02590003 ↗

Phase 2 Terminated 3 enrolled Yale University
RandomizedParallel-groupOpen-labelTreatment

Summary

This study will enroll elderly patients with advanced non-small cell lung cancer who are at high risk of developing chemotherapy toxicity (side effects). Patients will receive treatment with either a platinum-based doublet chemotherapy with carboplatin/nab-paclitaxel or single agent nab-paclitaxel of chemotherapy. Response to treatment and treatment toxicity will be compared in the two treatment groups to determine the best treatment strategy for this group of patients.

Timeline

Start
2015-11
Primary completion
2016-09
Completion
2016-09

Outcome

Outcome not reported

Stopped: “Trial was stopped after non-response to treatment.”

Drugs

EvaluationDrugModalityDoseRoute
Subject Carboplatin Small molecule — Intravenous
Subject Nab-paclitaxel Small molecule 100 mg/m2 Intravenous