drugset / Trial / NCT02595931

M6620 and Irinotecan Hydrochloride in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

NCT02595931

Phase 1 Active not recruiting 66 enrolled National Cancer Institute (NCI)
NaSingle-groupOpen-labelTreatment

Summary

This phase I trial studies the side effects and best dose of M6620 and irinotecan hydrochloride in treating patients with solid tumors that have spread to other places in the body (metastatic) or cannot be removed by surgery (unresectable). M6620 and irinotecan hydrochloride may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Timeline

Start
2016-07-22
Primary completion
2023-03-07
Completion
2027-03-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Berzosertib Small molecule Intravenous
Subject Irinotecan Small molecule Intravenous