drugset / Trial / NCT02595983

The Study of an Investigational Drug, Revusiran (ALN-TTRSC), for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis in Patients Whose Disease Has Continued to Worsen Following Liver Transplant

NCT02595983 ↗

Phase 2 Completed 12 enrolled Alnylam Pharmaceuticals
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study was to evaluate the safety and effectiveness of revusiran (ALN-TTRSC) in adults with transthyretin-mediated amyloidosis (ATTR), whose disease has continued to worsen after liver transplantation. Dosing has been discontinued; patients are being followed-up for safety.

Timeline

Start
2015-10
Primary completion
2017-02-06
Completion
2017-02-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Revusiran Small interfering RNA (siRNA) 500 mg Subcutaneous