drugset / Trial / NCT02596828
Prospective Pilot Trial to Assess a Multimodal Molecular Targeted Therapy in Children, Adolescent and Young Adults With Relapsed or Refractory High-grade Pineoblastoma
NaSingle-groupOpen-labelTreatment
Summary
Children, adolescents and young adults with relapsed or treatment refractory pineoblastoma (rPB) represent a group of patients with dismal prognosis for whom a recommended standard salvage therapy is currently not available.
Timeline
- Start
- 2016-04
- Primary completion
- 2021-04
- Completion
- 2021-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Rapamycin | Small molecule | — | Oral |
| Subject | dasatinib anhydrous | Small molecule | — | Oral |
| Background | Irinotecan | Small molecule | — | Intravenous |
| Background | Temozolomide | Small molecule | — | Oral |