The Efficacy of Intravenous Iron for the Treatment of Anemia in Cancer Patients

Summary

* Multifactorial pathogenesis is involved in anemia of cancer patients and defining the causes of anemia is not always simple. * Currently, treatment options available for anemia in cancer patients include red blood cell (RBC) transfusion, erythropoietin stimulating agent (ESA), and iron supplementation, accompanying considerable pros and cons for each treatment. * Previous studies have demonstrated benefit when treating with IV iron in combination with ESA and, more recently, evidence is emerging to suggest a role for IV iron alone. * In this study, investigator will assess the efficacy of intravenous iron for the treatment of anemia in cancer patients.

Timeline

Start

2015-09-12

Primary completion

2017-10

Completion

2017-12

Publications

• Jang JH, Kim Y, Park S, Kim K, Kim SJ, Kim WS, Jung CW, Lee J, Lee SH. Efficacy of intravenous iron treatment for chemotherapy-induced anemia: A prospective Phase II pilot clinical trial in South Korea. PLoS Med. 2020 Jun 8;17(6):e1003091. doi: 10.1371/journal.pmed.1003091. eCollection 2020 Jun.

Drugs

Indications