Regulation of Intestinal and Hepatic Lipoprotein Particle Production by Blood Glucose in Humans

Phase 2 Completed 10 enrolled University Health Network, Toronto

RandomizedCrossoverSingle-blindBasic science

Summary

The purpose of study is to examine whether raised blood glucose enhances lipid particle production independent of effects on gastric emptying and pancreatic/ gastrointestinal hormone production.

Timeline

Start: 2013-02
Primary completion: 2015-04
Completion: 2015-09

Publications

Xiao C, Dash S, Morgantini C, Lewis GF. Intravenous Glucose Acutely Stimulates Intestinal Lipoprotein Secretion in Healthy Humans. Arterioscler Thromb Vasc Biol. 2016 Jul;36(7):1457-63. doi: 10.1161/ATVBAHA.115.307044. Epub 2016 May 5.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Glucose	Unknown	20 %	Intravenous

Indications

No indication recorded.