drugset / Trial / NCT02612233
Pain Management in Osteoarthritis Using the Centrally Acting Analgesics Duloxetine and Pregabalin
RandomizedParallel-groupQuadruple-blindTreatment
Summary
Osteoarthritis is the most common form of arthritis worldwide. Specifically, osteoarthritis of the hands affects millions of people and is a major cause of hand disability and pain. Despite this, there are currently no treatments that delay or halt the development of osteoarthritis. Pain is one of the major symptoms of osteoarthritis and pain management is an important factor to consider in the treatment of this condition. Treatments for pain in osteoarthritis consists of local injections, anti-inflammatory gels or painkillers such as paracetamol. However, most people with osteoarthritis still have pain despite these treatments.
Timeline
- Start
- 2013-09
- Primary completion
- 2016-05
- Completion
- 2016-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Duloxetine | Small molecule | 60 mg | — |
| Comparator | Pregabalin | Small molecule | 300 mg | — |