drugset / Trial / NCT02612285

Study of SNX-5422 in TP53 Null Cancers

NCT02612285

Phase 2 Terminated 1 enrolled Esanex Inc.
NaSingle-groupOpen-labelTreatment

Summary

SNX-5422 is a pro-drug of SNX-2112, a potent, highly selective, small-molecule inhibitor of the molecular chaperone heat shock protein 90 (Hsp90). Initial in vitro evidence supports that SNX-5422 may be active against TP53 null tumors irrespective of tumor type .

Timeline

Start
2016-03
Primary completion
2016-10
Completion
2016-10

Drugs

EvaluationDrugModalityDoseRoute
Subject SNX-5422 Small molecule 100 mg/m2

Indications