drugset / Trial / NCT02612285
Study of SNX-5422 in TP53 Null Cancers
NaSingle-groupOpen-labelTreatment
Summary
SNX-5422 is a pro-drug of SNX-2112, a potent, highly selective, small-molecule inhibitor of the molecular chaperone heat shock protein 90 (Hsp90). Initial in vitro evidence supports that SNX-5422 may be active against TP53 null tumors irrespective of tumor type .
Timeline
- Start
- 2016-03
- Primary completion
- 2016-10
- Completion
- 2016-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | SNX-5422 | Small molecule | 100 mg/m2 | — |