drugset / Trial / NCT02619682

Alternating Ixazomib Citrate and Lenalidomide as Maintenance Therapy After Stem Cell Transplant in Treating Patients With Multiple Myeloma

NCT02619682

Phase 2 Completed 30 enrolled Fred Hutchinson Cancer Center
NaSingle-groupOpen-labelTreatment

Summary

This phase II trial studies the safety of alternating ixazomib citrate and lenalidomide as treatment to help keep cancer from coming back after stem cell transplant (maintenance therapy) in treating patients with multiple myeloma. Ixazomib citrate may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Lenalidomide may stimulate the immune system to attack cancer cells. Giving ixazomib citrate and lenalidomide as maintenance therapy after transplant may prolong the length of time until the cancer returns.

Timeline

Start
2015-12-30
Primary completion
2022-06-01
Completion
2025-10-24

Drugs

EvaluationDrugModalityDoseRoute
Subject Ixazomib Unknown Oral
Subject Lenalidomide Other / unclassified Oral