A Comparative Study of Intrathecal Magnesium Sulphate & Midazolam With Epidural Ropivacaine for Caesarean Patients

NCT02619799 ↗

Phase 2/3 Completed 50 enrolled Rangaraya Medical College

RandomizedParallel-groupDouble-blindTreatment

Summary

This study compares whether addition of Magnesium or Midazolam intrathecally to epidurally administered isobaric Ropivacaine improves the quality of blockade, haemodynamics and duration of analgesia post-operatively. 25 parturients were given intrathecal Magnesium and rest of the 25 parturients were given intrathecal Midazolam combined with 0.75% Ropivacaine via epidural route.

Timeline

Start: 2015-01
Primary completion: 2015-12
Completion: 2015-12

Publications

Background Culebras X, Gaggero G, Zatloukal J, Kern C, Marti RA. Advantages of intrathecal nalbuphine, compared with intrathecal morphine, after cesarean delivery: an evaluation of postoperative analgesia and adverse effects. Anesth Analg. 2000 Sep;91(3):601-5. doi: 10.1097/00000539-200009000-00019.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Magnesium Sulfate	Other / unclassified	50 mg	Intrathecal
Comparator	Midazolam	Small molecule	1 mg	Intrathecal

Indications

No indication recorded.