drugset / Trial / NCT02620384

Metolazone As Early Add On Therapy For Acute Decompensated Heart Failure (MELT-HF)--A Single Center Pilot Study.

NCT02620384

Phase 3 Terminated 147 enrolled Aultman Health Foundation
RandomizedParallel-groupTriple-blindTreatment

Summary

The primary objective of the study is to determine efficacy of metolazone as synergistic therapy with Lasix in patients with acute decompensated heart failure. This will be a single center double blinded randomized placebo- controlled pilot study of the addition of 5 mg of metolazone per day for 2 days compared to placebo in patients admitted with acute decompensated heart failure.

Timeline

Start
2015-10-01
Primary completion
2017-11-29
Completion
2017-12-29

Drugs

EvaluationDrugModalityDoseRoute
Comparator Metolazone Small molecule 5 mg

Indications