drugset / Trial / NCT02621957

Effect of GDC-0810 on the Pharmacokinetics of Pravastatin in Healthy Female Subjects of Non-Childbearing Potential

NCT02621957

Phase 1 Completed 15 enrolled Genentech, Inc.
NaSingle-groupOpen-labelBasic science

Summary

This study is to assess the pharmacokinetics (PK) of a single dose of pravastatin with and without concomitant GDC-0810 administration in healthy female subjects of non-childbearing potential. During Period 1 (Day -1 to Day 4) PK parameters of pravastatin will be determined in the absence of GDC-0810. During Period 2 (Days 5-28) PK parameters of pravastatin will be determined in the presence of GDC-0810.

Timeline

Start
2015-12
Primary completion
2016-02
Completion
2016-02

Drugs

EvaluationDrugModalityDoseRoute
Subject BRILANESTRANT Small molecule 600 mg Oral
Subject Pravastatin Small molecule 10 mg Oral

Indications