drugset / Trial / NCT02624440

Clarithromycin, Sulfamethoxazole/Trimethoprim or Observation in Newly Diagnosed Multiple Myeloma

NCT02624440

RandomizedParallel-groupOpen-labelTreatment

Summary

This study evaluates the effect of prophylactic antibiotics in multiple myeloma. One third of patients will received treatment with clarithromycin, one third of patients will receive treatment with sulfamethoxazole/trimethoprim and one third will be observed without prophylactic antibiotics. All patients receive concurrent anti-myeloma treatment.

Timeline

Start
2013-01
Primary completion
2016-07
Completion
2017-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Clarithromycin Small molecule 250 mg Oral
Subject Sulfamethoxazole/trimethoprim Unknown 80 mg Oral
Subject Sulfamethoxazole/trimethoprim Unknown 400 mg Oral