drugset / Trial / NCT02624453
Pre-Antiretroviral Therapy (ART) Cryptococcal Antigen Screening in AIDS
Unknown
186 enrolled
ANRS, Emerging Infectious Diseases
St George's, University of London · collabYaounde Central Hospital · collab
Non-randomizedParallel-groupOpen-labelScreening
Summary
The aim of the study is to evaluate systematic pre-antiretroviral cryptococcal antigen screening and pre-emptive fluconazole therapy in antigen positive patients, as a strategy to reduce morbidity and mortality due to AIDS associated cryptococcal meningitis in patients starting antiretroviral therapy at \<100 CD4 in Cameroon.
Timeline
- Start
- 2015-07
- Primary completion
- 2018-03
- Completion
- 2018-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Fluconazole | Small molecule | 200 mg | Oral |