Proton Pump Inhibitors Use in Patients With Psoriasis

Summary

Proton pump inhibitors act in blocking acid secretion and also have antioxidant and anti-inflammatory properties. For that mechanisms possibly PPIs may have an anti-inflammatory action with improvement in skin lesions in patients with psoriasis.

Timeline

Start

2016-01

Primary completion

2016-01

Completion

2016-12

Outcome

Outcome not reported

Stopped (Business): “Sponsor decision”

Publications

• Results Rahman M, Alam K, Ahmad MZ, Gupta G, Afzal M, Akhter S, Kazmi I, Jyoti, Ahmad FJ, Anwar F. Classical to current approach for treatment of psoriasis: a review. Endocr Metab Immune Disord Drug Targets. 2012 Sep;12(3):287-302. doi: 10.2174/187153012802002901.

Drugs

Indications