drugset / Trial / NCT02625779
Combined Cytidine and Creatine-containing Drug in the Treatment of the Bipolar Depression
RandomizedParallel-groupQuadruple-blindTreatment
Summary
This research is aimed to investigate the efficacy and safety of the creatine and cytidine augmentation in treating bipolar depression and to evaluate changes in relevant brain biochemical metabolism using proton and phosphorous magnetic resonance spectroscopy.
Timeline
- Start
- 2016-03-01
- Primary completion
- 2017-04-30
- Completion
- 2017-04-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Creatine-containing Drug | Unknown | 5 g | — |
| Subject | Cytidine-containing Drug | Unknown | 2 g | — |
| Comparator | Valproate | Small molecule | 300 mg | — |