drugset / Trial / NCT02631031

Chronopharmacology of Valsartan in Normotensive Subjects

NCT02631031

Phase 1 Completed 24 enrolled Ain Shams University
RandomizedCrossoverOpen-labelTreatment

Summary

The choice of drug administration time may affect the pharmacokinetics and/or drug response, and knowledge of any such circadian rhythm-dependent effects may help to reduce side effects or to enhance efficacy. This study designed to investigate the potential influence of the time of drug administration on the pharmacokinetics and pharmacodynamics of the valsartan in healthy subjects.

Timeline

Start
2015-11
Primary completion
2016-10
Completion
2017-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Valsartan Small molecule 160 mg Oral

Indications

No indication recorded.