Intrawound Vancomycin Powder in Spinal Fusion Surgery

Summary

Vancomycin powder (for solution for Infusion) will be investigated (off-label usage) in spinal fusion surgery. The powder will be locally administered into to the wound cavity before wound closure. Hypothesis: Locally applied vancomycin powder leads to a reduction in postoperative surgical site infections

Timeline

Start

2015-08

Primary completion

2019-03-01

Completion

2021-03-01

Publications

• Panzenbock LF, Abdel Nour G, Durrschnabel DL, Krepler P. Postoperative C-Reactive Protein Trajectories in Spine Surgery - Influence of Vancomycin Powder: A Secondary Analysis of a Prospective Randomized Controlled Trial. Global Spine J. 2026 May 8:21925682261450878. doi: 10.1177/21925682261450878. Online ahead of print.

Drugs

Indications