drugset / Trial / NCT02631694

Disruption of Memory Reconsolidating as a Treatment for Panic Disorder

NCT02631694

Phase 2 Unknown 60 enrolled VU University of Amsterdam
RandomizedParallel-groupTriple-blindTreatment

Summary

Animal and human fear conditioning studies have repeatedly shown that administering propranolol before or after retrieval of a previously acquired fear results in an elimination of the fear expression. This approach, known as disruption of fear memory reconsolidation, is a promising new avenue for treating anxiety disorders. The present study aims to test its efficacy in patients with panic disorder.

Timeline

Start
2016-04
Primary completion
2018-09
Completion
2019-09

Drugs

EvaluationDrugModalityDoseRoute
Subject Propranolol Small molecule 40 mg Oral

Indications